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Biology, epidemiology, and risk analysis in animal health (BioEpAR)

BioEpAR seeks to respond to the social demand and animal health managers expectations by providing key epidemio-economic background information for health management in farm animal populations and for veterinary public health control. MIHMES focuses on scientific issues that are pivotal to the group’s research, the pathogens of interest having been chosen based on the research and knowledge of the epidemiologists in the group.

BioEpAR coordinates the project. It is a mixed unit between INRA and ONIRIS, located in Nantes. It is a multidisciplinary group with special skills in modelling and computing (epidemiological modelling, population dynamics, decision modelling, simulation, model analysis), epidemiology (quantitative and molecular epidemiology, in cattle and pig), animal health management, animal health economics, biostatistics (classical biostatistics, spatial statistics), and immunology. Three teams are involved:

  • MODEC - modelling and decision - aims at better understanding and predicting pathogen spread and persistence in heterogeneous host populations to evaluate the epidemio-economic efficiency of prevention and control strategies. Models of the spread of BVDV, Map and Salmonella carriage in a cattle or pig herd have been developed by team MODEC in collaboration with MIA-Jouy. Research is based on a the development of a multi-scale modelling framework, from the within-host immune response to infection to pathogen spread and control between herds.
  • PVP - populations of vectors and parasites -aims at performing spatial and molecular analyses of pathogen populations to identify the relative contributions of the various routes of transmission in the between-herd spread of pathogens. PVP is particularly interested in Q fever control and the associated spread of Coxiella burnetii at a regional scale.
  • EPID - quantitative epidemiology -aims at describing health statuses of individual cattle and herds, identifying main factors of disease occurrence in cattle herds, and evaluating disease impact and efficiency of control measures at the herd or regional scale.

Project members


Pauline Ezanno

Scientific coordinator of MIHMES.

Co-supervisor of Bhagat Lal Dutta, Eric Breton, Gaël Beaunée, Pranav Pandit, Luyuan Qi Manager of Alix Damman, Guillaume Camanes and Fabrice Bidan.

Dr. P. Ezanno has skills in epidemiological modelling and population dynamics. She is involved mainly in WP1, WP2 and WP4.


François Beaudeau

Leader of WP1: from the individual to the population. Head of PVP.

Co-supervisor of Pranav Pandit. Supervisor of Simon Nusinovici.

Pr. Dr. F. Beaudeau has skills in cattle epidemiology and spatial statistics. He is involved mainly in WP1, WP2 and WP4.

Stéphane Krebs

Leader of WP3: predictive modelling to evaluate the epidemio-economic efficiency of control strategies.

Dr. S. Krebs has skills in animal health economics, especially in microeconomics. He is involved in WP3 and WP4.

Catherine Belloc

Team leader. Head of MODEC. Leader of WP4: From predictive modelling to decision tools.

Co-supervisor of Natacha Go and Eric Breton, Jordi Serrer-Saval

Dr. C. Belloc has skills in pig epidemiology and immunology. She also will provide support to apply economic models to real host/pathogen systems. She is concerned by all WPs.


Sandie Arnoux

Sandie Arnoux has skills in computer sciences, especially model and software development. She is involved in WP2 and WP4, and in relationships with partner Myriads. She manages the model and tool development of the project.


Florence Beaugrand

Florence Beaugrand deals with the efficiency of consultancy on animal health and is then involved in the users' motivations to use decision-making tools.

Alain Joly (GDS Bretagne)

Alain Joly has skills in animal health management.He has large relationships with the french socio-economic partners interested in cattle health management. He is involved in WP1, WP2 and WP4.


Raphaël Guatteo

Dr. R. Guatteo has skills in cattle epidemiology. He is involved mainly in WP1 and WP4.


Erwann Helleu

Erwann Helleu has skills in computer sciences, specifically in systems and networks administration. He is involved in managing the computing resources of the project tools.


Thierry Hoch

Co-supervisor of Pranav Pandit.

Dr. T. Hoch has skills in epidemiological modelling. He is involved mainly in WP2.


Mily Leblanc-Maridor


INRA, Oniris, BioEpAR (MODEC), Nantes

Funded by INRA

Dr. Mily Leblanc-Maridor is a contractual lecturer in swine and poultry medicine. She is involved in WP1 and WP2, especially concerning Salmonella in pigs.

Anne Lehebel

Anne Lehebel has skills in biostatistics. She is involved in WP1.


Aurélien Madouasse

INRA, Oniris, BioEpAR, Nantes

Funded by INRA

Dr. A. Madouasse is a contractual lecturer in epidemiology and animal health management. He is involved in WP2 and WP4.


Arnaud Rault

Dr. A. Rault is an economist and he has skills in the microeconomics of agricultural production. He is involved in the modelling of disease control decisions and strategies (WP3).


Henri Seegers
President of Angers-Nantes INRA centre. He is involved in WP4.

Pr. H. Seegers has skills in animal health management and veterinarian epidemiology. He is involved in WP2, WP3 and WP4.


Anne-France Viet

Dr. A-F. Viet has skills in computer sciences applied to epidemiology and decision making. She is involved mainly in WP3 and WP4.

See also

BioEpAR website

List of recent publications in line with the project.

Modification date: 11 September 2023 | Publication date: 27 September 2012 | By: MIHMES